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diagnosis algorithm causes transaminitis aptt coagulation prolonged pt acronym biliary chemistry cholangitis cirrhosis classification dermatology dili elevated elevatedmcv function gastroenterology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Tests (LFTs) - ... Differential Diagnosis ... 1000): • DILI (Drug-induced ... ) • Non-hepatic ... Diagnosis #hepatology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Volume (MCV) - Differential ... Blood Smear • Drugs ... Liver Function ... #elevatedMCV #Differential ... Algorithm #Causes #Hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Volume (MCV) - Differential ... Chronic Disease Normal ... Renal Disease, Liver ... Deficiency • Drugs ... Algorithm #Causes #Hematology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Idiosyncratic Drug-induced ... Chronic - ongoing ↑ LFTs ... Idiosyncratic #differential ... gastroenterology #hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... 15X ULN - Drugs ... Burak @kwburak #LFTs ... Algorithm #diagnosis #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... - Differential ... disease US — Normal ... • Others #LFTs ... #Hepatology #LiverEnzymes
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... , Liver Disease, ... Defects: Sickle cell anemia ... Blood Smear ↑ abnormal ... #Diagnosis #hematology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... replaced by non-hepatic ... chemistry #diagnosis #differential ... #Hepatology #transaminitis ... #LFTs #RValue #
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Secondary Causes: - Drug ... - Hemolytic anemia ... deficiency • Liver ... #Diagnosis #hematology
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... Drugs: Direct or ... • Reduced liver ... amyloidosis #Abnormal ... #hematology #coagulation
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