14 results
Petechial/Purpuric Rashes- THE ALGORITHMIC APPROACH 

These rashes can be especially challenging and are
associated with devastating differential
Nonpalpable purpura ... coagulopathy (DIC), or TTP ... rash, the diagnosis ... #Diagnosis #Dermatology ... #Purpuric #Rash
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
VS HUS Big picture ... Often hard to differentiate ... #purpura #TTP # ... #thrombocytopenia ... Diagnosis #Table #Hematology
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. 
TTP/HUS indicates thrombotic
for workup of thrombocytopenia ... TTP/HUS indicates ... purpura/hemolytic ... , Hematology 2012 ... #Diagnosis #Differential
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... /HUS - Hemolytic ... #Differential # ... rheumatology #palpable #nonpalpable ... #dermatology
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table

 • Thrombotic Thrombocytopenic Purpura (TTP)
Microangiopathy (TMA) - Differential ... • Thrombotic Thrombocytopenic ... Purpura (TTP) ... Microangiopathy #TMA #hematology ... #differential #
Causes of Purpura - Differential Diagnosis
Non-PalpabIe → Palpable
 • Thrombocytopenia (HIT, ITP/HUS), Coagulation defects (DIC, warfarin
Causes of Purpura ... - Differential ... → Palpable • Thrombocytopenia ... (HIT, ITP/HUS), ... #nonpalpable #palpable
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
- Differential ... hemostasis: - Thrombocytopenia ... - DIC - TTP ... #Differential # ... Algorithm #Causes #dermatology
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Approach to the differential ... glomerulonephritis; HUS ... = atypical HUS; ... glomerulonephritis; TTP ... = thrombotic thrombocytopenic
Bleeding manifestations 
Petechiae are small, flat, red, discrete areas of skin bleeding that are typically <2
non-blanching, nonpalpable ... individuals with thrombocytopenia ... blood normally has ... VWF:RCo/VWF:Ag (differentiate ... Bruise #ecchymosis #thrombocytopenia
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Petechiae • Purpura ... Subcutaneous dissecting hematoma ... DDX: • TMA’s (HUS ... /TTP/DITMA) - ... /HUS > DIC • Severe