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diagnosis differential rheumatology pain algorithm approach erythematosus lupus msk oncology sle systemic testing autoantibodies bone causes cirrhosis classification ear earpain
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... #Anemia #Differential ... Diagnosis #Algorithm #workup ... #hematology #testing
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
), RA, crystal disease ... Inflammatory, crystalline disease ... #rheumatology # ... approach #workup ... #differential #
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
Disease: • Pain ... disease must be ... #Pain #MSK #rheumatology ... #approach #workup ... #differential #
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... for workup, including ... blood loss, Acute hemolysis ... , deficiency anemia ... Vasculitides, IBD, Celiac disease
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Causes of Bone/Joint ... in Sickle Cell Disease ... predispose to other orthopedic ... Osteomyelitis / Septic Arthritis ... diagnosis #causes #hematology
Causes of Anemia in Cirrhosis - Differential Diagnosis Framework LOW RETIC INDEX - ↓ PRODUCTION • Vitamin
in Cirrhosis - Differential ... Peptic ulcer disease ... vascular ectasia, Hematomas ... anemia, Hemolysis ... #Diagnosis #Hepatology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
hallmark for the disease ... anemia Indirect ... WBC count and differential ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup ... #Hematology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Manifestations: - Arthritis ... Lymphadenopathies 7% - Hemolytic ... anemia 4% - Myositis ... (aPL) 30-45% Differential ... #rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... of the affected joint ... the presence of anemia ... • Sacroiliac joint ... #laboratory #workup
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... : • Joint pain ... arthropathy • 90% joints ... vein thrombosis Hematologic ... lymphopenia, low PLT • Anemia
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