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diagnosis differential rheumatology pain erythematosus msk sle systemic approach causes signs symptoms algorithm autoantibodies bone classification dermatology gap globulin inflammatory
Inflammatory Joint Pain - Differential Diagnosis Algorithm Monoarticular • Gout (Podagra, Tophi) • Pseudogout • Early
Inflammatory Joint ... Pain - Differential ... • Systemic Lupus ... JointPain #MSK #Differential ... Diagnosis #Algorithm #Orthopedics
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
), RA, crystal disease ... spondyloarthropathies, lupus ... #rheumatology # ... approach #workup ... #differential #
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Associated with Joint ... infection • Lyme disease ... lesions • Discoid lupus ... #joint #pain #skin ... #rashes #differential
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
Disease: • Pain ... disease must be ... #Pain #MSK #rheumatology ... #approach #workup ... #differential #
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Features of Systemic Lupus ... of hip (rare), Arthritis ... in small joints ... pain (20%) Renal disease ... ) Blood (75%): Anemia
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Manifestations: - Arthritis ... - Hemolytic anemia ... (aPL) 30-45% Differential ... sclerosis, Still's disease ... #rheumatology
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Causes of Bone/Joint ... in Sickle Cell Disease ... predispose to other orthopedic ... Osteomyelitis / Septic Arthritis ... diagnosis #causes #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Malignancy (e.g. hematologic ... : • Joint pain ... arthropathy • 90% joints ... lymphopenia, low PLT • Anemia
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... of the affected joint ... • Systemic lupus ... the presence of anemia ... #laboratory #workup
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitides - Differential ... inflammation Others: • Lupus ... vesicular eruption - Joints ... such as systemic lupus ... #diagnosis #rheumatology
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