16 results
diagnosis differential hematology causes anemia injury transaminitis classification mcv workup abnormal acute aflp bilirubinemia chemistry comparison disease elevated hepatocellular hyperbilirubinemia
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... 2-5x normal - Hemolysis ... #Injury #hepatology ... #LFTs #transaminitis ... #differential #
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Bilirubin: RBC (hemolysis ... , bleeding, hematoma ... LDH: Heart, RBC (hemolysis ... Gilbert's syndrome • Hemolysis ... #diagnosis #differential
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Syndrome (Hemolysis ... clinical features: Hemolysis ... Hepatic infarcts, Hematomas ... #obstetrics #hepatitis ... #comparison #differential
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... thrombocytopenia - DIC, TTP, HELLP ... elliptocytosis, autoimmune hemolysis ... ARUPConsult @ARUPLabs #Hemolytic
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
• Pregnancy: HELLP ... Gilbert's syndrome • Hemolysis ... Bilirubin: RBC (hemolysis ... LDH: Heart, RBC (hemolysis ... #hepatology
Isolated Hyperbilirubinemia - Differential Diagnosis Algorithm Direct Hyperbilirubinemia: Dubin-Johnson Syndrome, Rotor Syndrome Indirect Hyperbilirubinemia: - Trauma, Hematoma,
Hyperbilirubinemia - Differential ... Diagnosis Algorithm ... Hyperbilirubinemia: - Trauma, Hematoma ... Count Abnormal: Hemolysis ... #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
• Infections: Hepatitis ... NAFLD, Autoimmune, HELLP ... #Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... Pregnancy - AFLP, HELLP ... • Alcoholic hepatitis ... • Others #LFTs ... #Hepatology #LiverEnzymes
Pancytopenia - Differential Diagnosis Algorithm • 12-13 g/dL, • ANC < 1800/uL, • platelet < 150,000/uL Initial
Diagnosis Algorithm ... reticulocyte count, LFTs ... ↑ Destruction (hemolysis ... #Diagnosis #Algorithm ... #hematology #workup
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach ... -100): • Non-hemolytic ... anemia, CKD • Hemolytic ... Non-megaloblastic: Liver ... Diagnosis #hematology
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