19 results
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... deficiency • Liver ... vasculitis - GPA ... #Diagnosis #hematology ... #rheumatology #
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Joint Pain Rash ... infection Malar rash ... Sarcoidosis • GPA ... #skin #rashes #differential ... #diagnosis #rheumatology
ANCA-Associated Vasculitis
There are many definitions, but most come down to the presence of granulomas (pathologically or
pathologically or clinically ... polyangiitis (GPA ... polyangiitis (eGPA ... ANCA #Vasculitis #differential ... diagnosis #algorithm #rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Rarely dominate the clinical ... Maculopapular rash ... reticularis Differential ... #dermatology #rash ... #diagnosis #rheumatology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
weeks • Typical clinical ... post-partum • Typical clinical ... Hepatic infarcts, Hematomas ... Disease #Pregnancy #hepatology ... hepatitis #comparison #differential
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... disease: > 2 • NASH ... hemolysis, bleeding, hematoma ... injury #hepatitis #differential ... diagnosis #algorithm #hepatology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... arthritis, Skin rash ... fraction < 20% Differential ... management #treatment #rheumatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Liver Chemistries ... disease: > 2 • NASH ... hemolysis, bleeding, hematoma ... chemistry #diagnosis #differential ... #Hepatology #transaminitis
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
, Sarcoidosis, GPA ... polychondritis, GPA ... Hyperparathyroidism • Facial ... #joint #pain #differential ... #diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitides - Differential ... > PR3 60% • GPA ... mucositis - Rash ... • ANCA (Dx: GPA ... #diagnosis #rheumatology