11 results
Common toxicities of antifungal agents. 
CNS = central nervous system; 5-FC = flucytosine; GI = gastrointestinal;
CNS = central nervous ... SideEffects #Adverse #Pharmacology ... #InfectiousDiseases
Here is a quick guide on the common direct-acting antivirals (DAAs) for chronic hepatitis C virus
treatment #hcv #medications ... #infectiousdisease ... HepatitisC #Management #Pharmacology
Adjuvant therapies in critical care: steroids to treat infectious diseases
 - Severe Community Acquired Pneumonia
Corticosteroids #Adjuvant #InfectiousDiseases ... #Infections #Pharmacology ... Management #Treatment #Indications
Sedative-Hypnotic Drugs
Benzodiazepines:
 - Bind to specific GABAA receptor subunits at central nervous system (CNS) neuronal synapses
nervous system (CNS ... effects on the CNS ... effects on the CNS ... Hypnotic #Drugs #medications ... #pharmacology #
Drug-Induced Seizures - OTIS-CAMPBELL

O - Organophosphate, oral hypoglycemics, opioid
T - TCA, theophylline
I - Isoniazid, Insulin
S -
, Camphor, CO, CN ... Induced #Seizures #Medication ... #Differential #Pharmacology
Lyrica (Pregabalin) 
Indications: Neuropathy (diabetic, postherpetic neuralgia, fibromyalgia, & spinal cord injury), Adjunctive therapy for partial-onset
(Pregabalin) Indications ... Primary indications ... categorized as a C5 ... Lyrica #Pregabalin #Pharmacology
Opioid Use Disorder Medications - Pharmacokinetics

Buprenorphine is a partial mu-opioid receptor agonist with low intrinsic activity,
Opioid Use Disorder Medications ... with additional CNS ... margin of safety in pharmacology ... #UseDisorder #Medications ... Comparison #Table #Pharmacology
Hydroxychloroquine is an antimalarial & DMARD (disease modifying antirheumatic drug). It is currently being discussed as
has a number of CNS ... who require this medication ... Hydroxychloroquine #HCQ #Pharmacology
CSF Penetration of Antimicrobials

Despite the poor CSF penetration, beta-lactams have the most research documenting successful treatment
treat susceptible CNS ... in treatment of CNS ... #Penetration #CNS ... Antimicrobials #InfectiousDiseases ... #Pharmacology
Methadone Drug-Drug Interactions
Meds that increase methadone metabolism/decrease methadone effect (INCREASED RISK FOR OPIOID WITHDRAWAL):
 • Phenytoin,
St John’s Wort Medications ... INCREASED SEDATION/CNS ... Interactions #DDIs #pharmacology