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diagnosis hematology hemolytic agglutinin algorithm anemias antibody arteritis autoantibodies autoimmune classification cold disease erythematosus gca giantcell hiv hodgkins infections infectiousdiseases
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Diagnosis Algorithm Signs ... of anemia and hemolysis ... Immune-mediated Hemolysis ... Nonimmune-mediated Hemolysis ... #Anemias #Differential
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
AIHA • Anemia ... reticulocytes • Hemolysis ... • Blood smear: Differential ... #management #treatment ... #rheumatology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
anemia • Cold ... • Compensated hemolysis ... younger pts) Differential ... intravascular hemolysis ... #anemia #hematology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Lymphadenopathies 7% - Hemolytic ... anemia 4% - Myositis ... autoantibodies #signs ... #symptoms #mimickers ... rheumatology
Lung Infections in HIV - Differential Diagnosis Framework Disease by CD4 Count: Any CD4 Count: • Mycobacterium tuberculosis,
Hemoptysis (occasionally ... • CT: Halo sign ... and occasional hemoptysis ... 100% of cases), anemia ... Infections #HIV #AIDS
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
purpura: Strong sign ... < 30 years • Aorta ... pulmonary infiltrates, hemoptysis ... infiltrates/cavities, hemoptysis ... #Diagnosis #Rheumatology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
those coming off aorta ... very remarkable w/differential ... systemic complaints- anemia ... them, but urgent rheumatology ... #Management
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
nodosum • Immune hemolytic ... anemia • Pain ... ingestion • B symptoms ... Immunohistochemical studies (to differentiate ... #oncology #management
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