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rheumatology differential hemolytic sle algorithm anesthesia anesthesiology checklist classification druginduced erythematosus hemolysis intraoperative symptoms systemic treatment vasculitis antibody arteritis autoimmune
Hemolysis - Diagnostic Algorithm and Causes Increased red cell production: • Increased Reticulocytosis/polychromasia • Erythroid
Hemolysis - Diagnostic ... Algorithm and Causes ... #Hemolytic #Anemia ... #Workup #Hematology ... #Diagnosis *
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... usually IgG) (e.g. lupus ... Extravascular #Causes ... #hematology #anemia
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
1) DIAGNOSE AIHA ... reticulocytes • Hemolysis ... 2) LOOK FOR a cause ... #diagnosis #management ... #treatment #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Endocarditis, Aortic ... ) Blood (75%): Anemia ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... • Immunologic Workup ... Positive in 60-80% of cases ... Erythematosus #Diagnosis ... #rheumatology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
activity is the diagnostic ... hemorrhage and hemolysis ... result in severe anemia ... immune hemolytic anemia ... #Workup #Hematology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... Discontinuation of causal ... • Immunologic Workup ... Usual therapeutic management ... #diagnosis #management
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... - Differential Diagnosis ... primary or secondary hemostasis ... Autoimmune Vasculitis (lupus ... deficiency Work
High Central Neuraxial Block - Guidelines for Crises in Anaesthesia • Can occur with deliberate or accidental
of unrelieved aorto-caval ... that may mimic signs ... • Obstetric aorto-caval ... Intraoperative #Checklist #Diagnosis ... #Management #Workup
Intraoperative Cardiac Ischaemia - Guidelines for Crises in Anaesthesia If the patient is unconscious, signs of cardiac
Guidelines for Crises ... is unconscious, signs ... calcium. ❽ Treat anaemia ... Intraoperative #Checklist #Diagnosis ... #Management #Workup
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