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rheumatology differential erythematosus lupus symptoms testing vasculitis algorithm arteritis arthritis autoantibodies causes chronic cll criteria disease eularacr gca giantcell hemolytic
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Lupus (SLE) General ... Endocarditis, Aortic ... ) Blood (75%): Anemia ... #signs #symptoms ... #diagnosis #rheumatology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Criteria for Systemic ... Thrombocytopenia, Autoimmune hemolysis ... #Criteria #SLE ... Erythematosus #diagnosis
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... - Hemolytic anemia ... Lupusreference #SLE ... #Systemic #Lupus ... autoantibodies #signs
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... genotypes): SS, SC, SE ... elliptocytosis, autoimmune hemolysis ... #Algorithm #workup ... #hematology #testing
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Skin Disease Classification ... Differential Diagnosis ... lymphopenia, low PLT • Anemia ... Erythematosus #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
rendering the immune system ... Physical Exam/Signs ... • Neutropenia, anemia ... #workup #oncology ... #hematology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
those coming off aorta ... signs/sx of inflammation ... complaints- anemia ... them, but urgent rheumatology ... GCA #Temporal #Signs
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... purpura: strong sign ... vasculitis, and SLE ... #rheumatology # ... classification
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... affected joint • Systemic ... the presence of anemia ... (to support a diagnosis ... #diagnosis #testing
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... purpura: Strong sign ... < 30 years • Aorta ... Arteritis): • Aorta ... #Rheumatology
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