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diagnosis hematology algorithm hemolysis causes intravascular abnormal agglutinin anemias color discoloration disease nephrology testing urine workup
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Framework for Hemolysis ... Hemolysis: • ... Hemolysis: • ... EricsMedicalLectures/ #Hemolysis ... #Causes #differential
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Hemolysis - Differential ... and RES-mediated hemolysis ... - Hemolysis within ... anemia • ... malformations #Hemolysis
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Diagnosis Algorithm Signs ... of anemia and hemolysis ... Immune-mediated Hemolysis ... Nonimmune-mediated Hemolysis ... #Anemias #Differential
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral infection, autoimmune ... anemia • Cold ... • Compensated hemolysis ... younger pts) Differential ... hemolysis on rewarming
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Agglutination - Cold ... elliptocytosis, autoimmune ... hemolysis) ARUPConsult ... #Anemia #Differential
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Membrane): - Autoimmune ... : Warm AIHA, Cold ... Defects: Sickle cell anemia ... Urobilinogen #Hemolysis
Causes Abnormal Urine Color - Differential Diagnosis Turbid White Urine (Albinuria): • Chyluria, Filariasis, Schistosomiasis, Malignancy, Phosphaturia,
Urine Color - Differential ... mirabilis, E. coli ... hemolysis (G6PD ... deficiency, sickle cell anemia ... discoloration #Differential
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