225 results
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
suspect underlying hematologic ... disorders • Diagnosis ... #HES #Hematology ... #eosinophils #diagnosis ... #management #algorithm
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... ) - HELLP syndrome ... Hemolytic uremic syndrome ... #hematology #anemia
Hemolysis - Diagnostic Algorithm and Causes

Increased red cell production: 
 • Increased Reticulocytosis/polychromasia 
 • Erythroid
Hemolysis - Diagnostic ... Algorithm and Causes ... #Differential #Causes ... #Workup #Hematology ... #Diagnosis *
Jaundice - Differential Diagnosis Algorithm
Pre-Hepatic - Unconjugated Hyperbilirubinemia
Increased Production
 • Hemolysis
 • Ineffective Erythropoiesis
 • Hematoma
Decreased
- Differential Diagnosis ... Production • Hemolysis ... • Gilbert's Syndrome ... #Algorithm #Causes ... #Hepatology #bilirubinemia
Causes of Erythema Nodosum - Mnemonic

NO cause found in 60% of cases
Drugs (antibiotics e.g., sulfonamides, amoxicillin)
Oral
Causes of Erythema ... Sarcoidosis or Lofgren's syndrome ... Nodosum #Mnemonic #Causes ... #Differential #Diagnosis ... #Dermatology #SkinRash
Differential diagnosis of schistocytes / fragmentation hemolysis:
 • Thrombotic microangiopathies (TMA)
    - TTP
Differential diagnosis ... hemolytic-uremic syndrome ... anemia" • HELLP syndrome ... #differential #diagnosis ... #hematology #hemolysis
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Causes of Thrombocytosis ... - Differential Diagnosis ... iron deficiency, hemolysis ... Myelodysplastic syndrome ... #Causes #hematology
Causes of Hemoptysis - Differential Diagnosis Algorithm
Massive Hemoptysis (>I00 mL in 24 hours)
 • Malignancy
 •
Causes of Hemoptysis ... - Differential Diagnosis ... Goodpasture's Syndrome ... #Differential #Diagnosis ... #Algorithm #Causes
Hemoptysis - Differential Diagnosis Framework
Airways: 
 • Bronchitis
 • Bronchiectasis
 • Malignancy: Primary bronchogenic CA, Endobronchial
Hemoptysis - Differential ... Diagnosis Framework ... Osler-Weber-Rendu syndrome ... #Differential #Diagnosis ... #pulmonary #causes
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Causes of Extravascular ... - Differential Diagnosis ... #Differential #Diagnosis ... #Algorithm #Causes ... #Hematology