475 results
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
Synthesis: in hepatocyte ... accumulation in hepatocyte ... from albumin upon hepatocyte ... conjugation in hepatocyte ... reuptake into hepatocyte
Pathology - Hepatocyte Pigments

Lipofuschin (H&E) 

Alpha-I-antitrypsin globules (PAS-D) 

Mallory's hyaline / Mallory Denk Bodies 

Giant Mitochondria
Pathology - Hepatocyte ... bilirubinostasis (H&E) #Hepatocyte
Daptomycin  - Antibiotics Class Overview

Mechanism: Lipopeptide antibiotic – forms transmembrane channels and depolarizes cells.
Antibiotics Class Overview ... gram negative activity ... Antibiotics #Review #Overview
Linezolid (Zyvox) (PO and IV) - Antibiotics Class Overview

Mechanism: Oxazolidinone class –unique ribosomal inhibitor (acts on
Antibiotics Class Overview ... Also has good activity ... Antibiotics #Review #Overview
The Mechanism of Small Interfering RNA (siRNA) Therapy. Synthetic double-stranded RNA containing an ALAS1-specific sequence is
exclusively on hepatocytes ... Within the hepatocyte
Aminoglycosides  - Antibiotics Class Overview

Gentamicin, Tobramycin, Amikacin, Streptomycin -30S inhibitor (all IV)
Spectrum: Extremely efficacious vs.
Antibiotics Class Overview ... NO activity vs. ... Antibiotics #Review #Overview
Ivermectin. Old anti-parasitic agent making a comeback with recent headlines from in-vitro study that showed antiviral
showed antiviral activity ... here is a quick overview
Vancomycin and Dalbavancin (lipoglycopeptide antibiotics) - Antibiotics Class Overview

Mechanism: Glycopeptide -  inhibits cell wall synthesis
Antibiotics Class Overview ... positive agent with activity ... Antibiotics #Review #Overview
Sepsis Treatment Overview #Management #EM #IM #PCC #Sepsis #Overview #BMJ
Sepsis Treatment Overview ... #PCC #Sepsis #Overview
ANTIBIOTICS WITH ANAEROBE COVERAGE - Antibiotics Class Overview
 1. Metronidazole (Flagyl)(PO and IV)
 2. Clindamycin –
Antibiotics Class Overview ... as it also has activity ... excellent anaerobic activity ... excellent anaerobic activity ... Antibiotics #Review #Overview