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diagnosis hematology differential clinical algorithm management dermatology rash causes treatment video physicalexam anemia msk photo skin syndrome pathophysiology vasculitis workup
Histologic Features and Prevalence of Nonalcoholic Steatohepatitis (NASH). NASH is a potentially progressive type of nonalcoholic
Steatohepatitis (NASH ... NASH is a potentially ... specimens: ballooned hepatocytes ... distribution of NASH ... #Epidemiology #NASH
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism AST and ALT: • AST: liver
Synthesis: in hepatocyte ... accumulation in hepatocyte ... from albumin upon hepatocyte ... conjugation in hepatocyte ... reuptake into hepatocyte
Pathogenesis of Nonalcoholic Steatohepatitis. Various factors, including inflammation, hyperinsulinemia or insulin resistance, and altered lipid homeostasis,
develop in fatty hepatocytes ... Pathophysiology #GI #IM #NASH
Pathology - Hepatocyte Pigments Lipofuschin (H&E) Alpha-I-antitrypsin globules (PAS-D) Mallory's hyaline / Mallory Denk Bodies Giant Mitochondria
Pathology - Hepatocyte ... bilirubinostasis (H&E) #Hepatocyte
The Mechanism of Small Interfering RNA (siRNA) Therapy. Synthetic double-stranded RNA containing an ALAS1-specific sequence is
exclusively on hepatocytes ... Within the hepatocyte
Thrombotic Microangiopathies In Systemic Lupus Erythematosus Dr. Laurent ARNAUD @Lupusreference #TMAs #Thrombotic #Microangiopathies #Systemic #Lupus #Erythematosus #SLE #hematology
Erythematosus #SLE #hematology ... #rheumatology #
I’M DAMN SHARP - Lupus Diagnosis Mnemonic I Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid) M Malar Rash D
Anti-phospholipid) M Malar Rash ... D Discoid Rash ... erythematosus #rheumatology
NAFLD Activity Score (NAS) 0–3 for steatosis 0–3 for inflammation 0–2 for ballooning hepatocytes NAS ≥5 is classified as definitive
Activity Score (NAS ... for ballooning hepatocytes ... NAS ≥5 is classified ... as definitive NASH ... Activity #Score #NAS
NAFLD / NASH Progression Timeline Healthy Liver → NAFLD/NASH → 0.25-3.2%/year → Cirrhotic NASH → 0.3-2.6%/year →
NAFLD / NASH Progression ... Liver → NAFLD/NASH ... year → Cirrhotic NASH ... → HCC • NAFLD/NASH ... → Cirrhotic NASH
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
can present with rash ... including heliotrope rash ... Myositis #diagnosis #rheumatology
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