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diagnosis differential algorithm causes hematology management clinical pathophysiology symptoms nephrology signs neurology workup endocrinology treatment physicalexam cardiology pharmacology hemolytic pulmonary
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Microcytic - Iron-deficiency ... Spherocytes - Hereditary ... Elliptocytes - Hereditary ... Thalassemia, Iron-deficiency ... cells - G-6-PD deficiency
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
RBC: Pyridoxine deficiency ... Thalassemia, Iron deficiency ... drugs Elliptocyte: Hereditary ... : Hereditary spherocytosis ... Stomatocyte: Hereditary
Elliptocyte - Note the shape of these appropriately named erythrocytes. In addition to hereditary elliptocytosis, elliptocytes can
In addition to hereditary ... megaloblastic anemia ... myelophthisic anemia ... and severe iron deficiency ... anemia.
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
Hemolytic Anemia ... Diagnosis Algorithm Hereditary ... DAT (-) → G6PD Deficiency ... → Sickle Cell anemia ... → Hereditary spherocytosis
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... ' nucleotidase deficiency ... membrane disorder (hereditary ... spherocytosis, hereditary ... ARUPLabs #Hemolytic #Anemia
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Defects • Hereditary ... spherocytosis • Hereditary ... Defects • G6PD deficiency ... • PK deficiency ... immune-complex hemolytic anemia
Koilonychia in Iron-Deficiency Anemia- A 54-year-old woman presented to the primary care clinic with fatigue and
Koilonychia in Iron-Deficiency ... Anemia- A 54-year-old ... anemia and may ... also be hereditary ... #anemia #nails
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Microangiopathic hemolytic anemia ... G6PD deficiency) ... defects (e.g. hereditary ... diagnosis #hematology #anemia
Causes of Hyperkalemia l. Pseudohyperkalemia A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis B.
Hereditary defects ... ), sickle cell anemia ... amyloidosis, sickle cell anemia ... Hereditary: adrenal ... aldosterone synthase deficiency
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
malignancy, or thiamine deficiency ... 30mmHg) - Severe anemia ... effect - Thiamine deficiency ... Propofol • Type B3: Hereditary
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