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Facial Swelling from Hereditary Angioedema on Physical Examination

19 year old Hereditary Angioedema (HAE) patient from Turkey.
Swelling from Hereditary ... Angioedema on Physical ... 19 year old Hereditary ... Angioedema (HAE ... #Angioedema #clinical
Angioedema - Classification Diagnosis and Treatment
Types of Angioedema:
 • Acute allergic angioedema - Usually occurs with
Angioedema - Classification ... Treatment Types of Angioedema ... Acute allergic angioedema ... urticaria • Hereditary ... angioedema - Rare
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Iron deficiency anemia ... Chronic disease anemia ... drugs Elliptocyte: Hereditary ... Spherocyte: Hereditary ... Stomatocyte: Hereditary
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Iron-deficiency anemia ... Sideroblastic anemia ... Megaloblastic anemia ... Spherocytes - Hereditary ... Elliptocytes - Hereditary
Hemolytic Anemia - Differential Diagnosis Algorithm
Hereditary:
 • Peripheral blood smear + DAT + further History
 •
Hemolytic Anemia ... Diagnosis Algorithm Hereditary ... → Sickle Cell anemia ... → Hereditary spherocytosis ... Microangiopathic hemolytic anemia
Elliptocyte - 
Note the shape of these appropriately named erythrocytes.
In addition to hereditary elliptocytosis, elliptocytes can
In addition to hereditary ... megaloblastic anemia ... myelophthisic anemia ... sideroblastic anemia ... iron deficiency anemia
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
deposition disease, hereditary ... angioedema A -
Differential Diagnosis of Anemias #Diagnosis #IM #Honc #Anemia #Differential #Iron #Algorithm #Microcytic #Macrocytic #Normocytic #Ddxof
Differential Diagnosis of Anemias ... Diagnosis #IM #Honc #Anemia
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... membrane disorder (hereditary ... spherocytosis, hereditary ... ARUPLabs #Hemolytic #Anemia
Effect of Selected Diseases on Complement Levels - C3, C4
 • SLE C3 ↓ C4 ↓↓
C3 ↓ C4 ↓↓ • Hereditary ... angiooedema C3