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diagnosis rheumatology lupus sle table treatment vasculitis activation adultonset classification compared dermatology disease druginduced erythemas macrophage mas neurology neurosarcoidosis signs
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... 40, F:M 9:1 • Clinical ... Manifestations: Malar rash ... #Erythematosus ... #Summary #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... (SLE) General: ... Photosensitivity, Butterfly rash ... #erythematosus ... symptoms #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Suspect: Clinical ... permanent alopecia Differential ... lymphoproliferative syndrome Clinical ... Neuropsychiatric systemic
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
lupus erythematosus ... Petechial or purpuric rash ... lupus erythematosus ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... arthritis, Skin rash ... fraction < 20% Differential ... solid cancers • Systemic ... Disease #diagnosis #management
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... NPSLE rare, Malar rash ... months to years) Systemic ... Lupus Erythematosus ... druginduced #lupus #sle #comparison
Erythemas Summarized Erythema ab igne • A dermatosis that results from repeated exposure to heat (fires, heating
(cutaneous or systemic ... presenting with erythematous ... multiforme • Acute systemic ... PrathitKulkarni #Erythemas #comparison ... #table #differential
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitides - Differential ... ischemia - Skin: erythematous ... mucositis - Rash ... lupus erythematosus ... #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... Vasculitis Differential ... ischemia • Skin: Erythematous ... , mucositis • Rash ... #Diagnosis #Rheumatology
Neurosarcoidosis - Diagnosis and Treatment • 5 to 40% of sarcoidosis, Heterogeneous, often inaugural • Central
inaugural • Central ... Nervous System ... neurosarcoidosis: Clinical ... , Exclusion of Differential ... Diagnosis #Treatment #management
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