14 results
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE ... • Immunologic Workup ... pANCA anti-MPO - Negative ... life-threatening • Treatment ... Management #Summary #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... constitutional symptoms • Treatment ... • Immunologic Workup ... pANCA anti-MPO - Negative ... life-threatening • Treatment
Capnocytophaga
Pathogen: Capnocytophaga
 • 9 species, C. canimorsus responsible for the majority of infections
 • Gram-negative rod,
infections • Gram-negative ... ), Malignancy, SLE ... fusiform gram-negative ... Treatment: • 50% ... microbiology #zoonotic #infectiousdiseases
Blood Culture-Negative Infective Endocarditis (BCNIE)
Definition: No etiology found after 3 separate blood cultures remain negative for
Blood Culture-Negative ... microbiological techniques Work-up ... See charts - ... #differential #workup ... #infectiousdiseases
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
• Some false negative ... with response to treatment ... IgG4+ cells" Treatment ... management #phenotypes #workup ... #treatment #rheumatology
Coccidiomycosis - Diagnosis
Diagnosis:
 • Mildly elevated peripheral WBC, Eosinophilia (25%), Elevated ESR, Procalcitonin normal (95%)
 •
trend response to treatment ... Culture (ElA may be negative ... Coccidioides #Diagnosis #workup ... #infectiousdiseases
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... erythematosus (SLE ... ANAs; thus, a negative ... Arthritis #laboratory #workup ... diagnosis #testing #Rheumatology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Skin findings: Hidradenitis ... affected areas and if negative ... and lower jaw Treatment ... SAPHO #Syndrome #Rheumatology ... diagnosis #management #Dermatology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... microglobulin Treatment ... Leukemia #diagnosis #workup ... #oncology #hematology
"Scrotal Pain + Uganda:Almost never see it in the developed world unless you are like this
Uganda:Almost never see ... infectious despite negative ... See the multiple ... some experimental treatment ... POCUS #Urology #InfectiousDiseases