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diagnosis management rheumatology differential druginduced endocarditis arthritis bcnie bloodculture canimorsus capnocytophaga cardiology clinical cocci coccidioides coccidioidomycosis comparison dil disease erythematosus
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... , oral ulcers, Lupus ... • Immunologic Workup ... pANCA anti-MPO - Negative ... life-threatening • Treatment
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... constitutional symptoms • Treatment ... • Immunologic Workup ... pANCA anti-MPO - Negative ... life-threatening • Treatment
Capnocytophaga Pathogen: Capnocytophaga • 9 species, C. canimorsus responsible for the majority of infections • Gram-negative rod,
infections • Gram-negative ... ), Malignancy, SLE ... fusiform gram-negative ... Treatment: • 50% ... microbiology #zoonotic #infectiousdiseases
Blood Culture-Negative Infective Endocarditis (BCNIE) Definition: No etiology found after 3 separate blood cultures remain negative for
Blood Culture-Negative ... microbiological techniques Work-up ... See charts - ... #differential #workup ... #infectiousdiseases
Coccidiomycosis - Diagnosis Diagnosis: • Mildly elevated peripheral WBC, Eosinophilia (25%), Elevated ESR, Procalcitonin normal (95%) •
trend response to treatment ... Culture (ElA may be negative ... Coccidioides #Diagnosis #workup ... #infectiousdiseases
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... joint • Systemic lupus ... erythematosus (SLE ... ANAs; thus, a negative ... Arthritis #laboratory #workup
"Scrotal Pain + Uganda:Almost never see it in the developed world unless you are like this
Uganda:Almost never see ... infectious despite negative ... See the multiple ... some experimental treatment ... POCUS #Urology #InfectiousDiseases
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 Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Drug Induced Lupus ... is rare in DIL, SCLE-DIL ... • Immunologic Workup ... constitutional symptoms • Treatment ... rheumatology #diagnosis #treatment
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
• Autoimmune (SLE ... aureus, Coagulase-negative ... staphylococci Culture Negative ... hematuria, + RF Treatment ... Diagnosis #cardiology #infectiousdiseases
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