7 results
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
- Differential ... , CKD • Hemolytic ... Macroangiopathic, Infections ... #Differential # ... Diagnosis #hematology
Autoimmune Hemolytic Anemia (AIHA)

WARM AHA
- Primary - Idiopathics
- Secondary
Infectious
 • Viral- HIV, EBV, HCV, HEV
 •
Autoimmune Hemolytic ... Anemia (AIHA) ... Viral- HIV, EBV, HCV ... • Parasitic- Babesia ... Diagnosis #Differential
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
for Hemolytic Anemia ... drug induced • Infections ... Bartonella, Babesia ... #Anemia #Differential ... classification #hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Corpuscular Volume (MCV ... ) - Differential ... • Bleeding • Hemolysis ... Inflammation, Chronic Infection ... Algorithm #Causes #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... inclusions - If infection ... (oroya fever), babesia ... #Anemia #Differential ... Algorithm #workup #hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
B12, Folate • Hormone ... (e.g. cancer, infection ... Microangiopathic hemolytic ... Production #Index #hematology ... #anemia #differential
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... DIC/TTP/HUS - Hemolytic ... anemia - Splenomegaly ... SLE) - Viral infections ... • HCV, HBV Not