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diagnosis hematology causes hemolytic thrombocytopenia agglutinin algorithm alopecia calculation classification cold disease disorders gap globulin hair hairloss index loss nonpalpable
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
B12, Folate • Hormone ... (e.g. cancer, infection ... G6PD deficiency), Infections ... Production #Index #hematology ... #anemia #differential
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Thrombocytopenia - Differential ... Megakaryopoiesis • Aplastic Anemia ... Quinidine • HIT ... Vasculitis • Infection ... Algorithm #Causes #Hematology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... drug induced • Infections ... #Differential # ... classification #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
- Due to Viral infection ... Polyclonal - Viral Infection ... Check For: • Infections ... Polyclonal IgM post infectious ... Mycoplasma, EBV, HIV
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... - Hemolytic anemia ... SLE) - Viral infections ... APLS • Acute Infectious ... • HCV, HBV Not
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... procedures - Infection ... changes), high MCV anemia ... Platelet #Disorders #Differential ... Causes #Workup #hematology
Allopecia - Differential Diagnosis Framework for Hair Loss Localized / Focal Hair Loss Pattern: • Scarring Alopecia:
Alopecia: - Infectious ... Post op, Post infection ... adenopathy suggest infection ... Dermatitis (Consider HIV ... #Diagnosis #dermatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Include: • Viral infections ... (acute HIV, HBV ... Thalassemia, Sickle cell anemia ... Gap #ProteinGap #differential ... #diagnosis #hematology
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