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algorithm oncology rheumatology systemic generalized hemolytic pruritus secondary chronic cll disorders erythematosus gap globulin gpa granulomatosis hemolysis intravascular leukemia lupus
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Causes Intravascular ... thrombocytopenic purpura (TTP ... e.g. lupus, CLL, lymphoma ... #Causes #differential ... #diagnosis #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
of cases) Classification ... Lymphoma Workup ... Immunohistochemical studies (to differentiate ... #lymphoma #diagnosis ... #hematology #oncology
Skin Ulcers by Etiology - Differential Diagnosis Algorithm Physical: • Trauma • Pressure • Radiation Vascular: • Arterial
cutaneous T-cell lymphoma ... • Bleomycin Hematologic ... • Sickle Cell Anemia ... #dermatology #Differential ... #causes
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... : TTP, HUS, DIC, ... Diagnosis #causes ... #classification ... #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... - Hemolytic anemia ... #Diagnosis #hematology ... #nonpalpable #dermatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... GPA causes disease ... • Goodpasture syndrome ... vasculitis #Dermatologic ... Polyangiitis #GPA #dermatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... • Nonmalignant hematologic ... hemolysis, deficiency anemia ... #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... changes), high MCV anemia ... or if a primary hematologic ... #Diagnosis #Causes ... #Workup #hematology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Diagnosis Algorithm ... : • Lymphoma ... Myelodisplastic syndrome ... #generalized #dermatology ... #causes
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
identical to the non-Hodgkin ... • Neutropenia, anemia ... cell aplasia • ITP ... #workup #oncology ... #hematology
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