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hematology hemolytic rheumatology arterial bruising embolism gpa granulomatosis hemolysis nonpalpable palpable pathophysiology pediatrics peds polyangiitis rash thrombocytopenia thrombosis thromboticthrombocytopenicpurpura vascular
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Causes Intravascular ... thrombocytopenic purpura ... (TTP), Hemolytic ... #Causes #differential ... #diagnosis #hematology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... IVIG infusion Intravascular ... : TTP, HUS, DIC, ... Diagnosis #causes ... #classification
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... - Hemolytic anemia ... Diagnosis #hematology ... #nonpalpable #dermatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... GPA causes disease ... Necrotising vasculitis, extravascular ... vasculitis #Dermatologic ... Polyangiitis #GPA #dermatology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... Thrombocytopenic Purpura ... reflection of intravascular ... WBC count and differential ... #Workup #Hematology
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
Causes of Purpura ... Immune - ITP ... (disseminated intravascular ... peds #pediatrics #diagnosis ... #differential #
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Hyperviscosity, TTP ... • Nephrotic Syndrome ... - Disseminated intravascular ... coagulation and other causes ... of purpura fulminans
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