11 results
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Agents to Treat Hyperkalemia ... magnesium, and calcium ... patients sensitive to high ... Potassium #Binding #Hyperkalemia ... #pharmacology #table
Hypercalcemia Evaluation
1) Clinical clues
 - Is the patient symptomatic?
 - Family history?
 - Have you done
Hypercalcemia Evaluation ... PTH - Frankly high ... BrighamChiefs #Hypercalcemia ... #workup #differential ... endocrinology #calcium
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
abnormalities - Hypercalcemia ... Hypomagnesemia #Differential ... Low #Magnesium #Table ... #Classification ... #Causes #Workup
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - Differential ... • LDH ↑ • Hyperkalemia ... /Late - Hypercalcemia ... potassium and calcium ... Dialysis for severe hyperkalemia
Types of Renal Calculi

Calcium oxalate
 - Interstitial apatite plaque, Low urine volume, Increased urinary calcium excretion,
hypercalciuria, Hypercalcemia ... hypercalciuria, Hypercalcemia ... Mycoplasma infections, High ... - Antiviral treatment ... #diagnosis #causes
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
immature blasts and high ... WBC count cause ... hydration - Hyperkalemia ... treatment (no calcium ... phos binders
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... : • Calcium 2- ... emcrit.org/ibcc/hyperkalemia ... management of hyperkalemia ... #Hyperkalemia
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Rhabdomyolysis - Differential ... potassium and calcium ... Dialysis for severe hyperkalemia ... Management #Summary #causes ... #treatment
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Pump - Digoxin works ... causes: - Increased ... - Hyperkalemia ( ... high potassium levels ... Because digoxin binds
Intraoperative  Bradycardia - Guidelines for Crises in Anaesthesia
Bradycardia in theatre should not be treated as
remember to tailor treatment ... Consider known drug causes ... Also consider: high ... myocardial infarction, hyperkalaemia ... Diagnosis #Management #Workup