15 results
Causes of Hypercalcemia
Hypercalcemia due to increased bone Ca2+ resorption:
 • Primary hyperparathyroidism, Malignancy, Pseudohyperparathyroidism, Renal failure,
Causes of Hypercalcemia ... Hypercalcemia ... Immobilization Hypercalcemia ... hypocalciuria, Thiazides Hypercalcemia ... intoxication #Hypercalcemia
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
- Differential ... Diagnosis Framework HEMATOLOGIC ... Hyperphosphatemia • Hyperkalemia ... renal failure • Hypocalcemia ... Hypercalcemia
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
• LDH ↑ • Hyperkalemia ... Hyperphosphatemia • Hypocalcemia ... /Late - Hypercalcemia ... UA positive for blood ... Dialysis for severe hyperkalemia
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
Cancer Related • Hypercalcemia ... change disease • Hematologic ... malignancies Treatment ... #AKI #Cancer #Oncology ... #Differential #
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Hypertension - Workup and Differential ... disorders including hypokalemia ... Vasculitis • Endocrinologic ... Hyperthyroidism, Hypercalcemia ... Workup #causes #Differential
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
Gammopathies C - HyperCalcemia ... plasmacytoma, POEMs syndrome ... MGUS #diagnosis #hematology ... #oncology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
immature blasts and high ... organ damage • Treatment ... Spontaneous if high ... hydration - Hyperkalemia ... diagnosis #management #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... • Attempt if high ... initiation • Differential ... diagnosis #management #hematology ... #oncology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
factor (GCSF) treatments ... count with differential ... marrow studies Treatment ... #diagnosis #hematology ... #oncology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Hypertensive emergency, Blood ... transfusion, Hypercalcemia ... Reversible course Differential ... elevated white blood ... epilepticus Treatment