13 results
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
(TLS) and Treatment ... other symptomatic hypocalcemia ... Treatment of TLS ... hydroxide • Hyperkalemia ... • Hypocalcemia
Reflex Testing - Causes of Hyporeflexia and Hyperreflexia
Focal Hyporeflexia: 
 • Radiculopathy, Mononeuropathy, Polyneuropathy, Acute stroke,
Polyneuropathy, Acute ... Hyporeflexia: • Hypercalcemia ... , Hypermagnesemia ... Hyperreflexia: • Hypocalcemia ... Testing #Causes #differential
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
• LDH ↑ • Hyperkalemia ... Hyperphosphatemia • Hypocalcemia ... /Late - Hypercalcemia ... Monitor potassium ... Dialysis for severe hyperkalemia
Tumor Lysis Syndrome
An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... 6L/day) • For hyperkalemia ... otherwise treat with "hyperkalemia ... #TLS #oncology ... #management #UricAcid
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
Acute Kidney Injury ... Cancer Related • Hypercalcemia ... malignancies Treatment ... Cancer #Oncology #Differential ... #Diagnosis #Classification
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
immature blasts and high ... - ACS, AKI, acute ... hydration - Hyperkalemia ... #TLS #diagnosis ... #management #hematology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Family history of hypokalemia ... • Unexplained hypokalemia ... pressure Labs: • Hypokalemia ... ratio 0.5%) Differential ... pathophysiology #Hypokalemia
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Rhabdomyolysis - Differential ... Diagnosis and Management ... HIV, Influenza, TSS ... Monitor potassium ... Dialysis for severe hyperkalemia
Causes of Hyperkalemia
l. Pseudohyperkalemia
  A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis
  B.
Causes of Hyperkalemia ... axis; T risk of hyperkalemia ... #Hyperkalemia ... #Differential # ... #Potassium #Classification
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
irrigation • Management ... Loop Diuretics; High-Ceiling ... Torsemide) • Acute ... Hyponatremia • Hypercalcemia ... Tolvaptan) • Treatment