31 results
Workup of Hypercalcemia - Differential Diagnosis Algorithm
High or Normal PTH:
 • Hyperparathyroidism: Parathyroid adenoma, Parathyroid hyperplasia,
Workup of Hypercalcemia ... Hypocalciuric Hypercalcemia ... calcitriol induced hypercalcemia ... Infantile idiopathic hypercalcemia ... @aishaikh #Hypercalcemia
Pathophysiology of Tumor Lysis Syndrome (TLS)
Tumor Cell Lysis
-> Release of DNA
 • Purines -> Hypoxanthine /
Pathophysiology ... of Tumor Lysis Syndrome ... -> Uric Acid (low ... urine pH) • Hypocalcemia ... • Hyperkalemia
Hypomagnesemia - Differential Diagnosis
Renal Causes of Hypomagnesemia - Familial:
Bartter syndrome and Gitelman syndrome, Isolated recessive hypomagnesemia,
Hypomagnesemia - Differential ... and Gitelman syndrome ... with secondary, hypocalcemia ... pentamidine), Hypercalcemia ... nephrology #magnesium #low
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
abnormalities - Hypercalcemia ... - Hypokalemia ... - Hungry bones syndrome ... Hypomagnesemia #Differential ... #Diagnosis #Low
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
of Tumor Lysis Syndrome ... other symptomatic hypocalcemia ... hydroxide • Hyperkalemia ... • Hypocalcemia ... TLS #diagnosis #management
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Framework and Management ... • LDH ↑ • Hyperkalemia ... Hyperphosphatemia • Hypocalcemia ... /Late - Hypercalcemia ... Dialysis for severe hyperkalemia
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Causes of Hypokalemia ... - Refeeding Syndrome ... #Hypokalemia ... causes #potassium #low ... #pathophysiology
Cancer agents and Electrolyte Disorders
 • Hypocalcemia: Cisplatin from Low Mg, Cetuximab- due to low Mg
Axitinib,
Disorders • Hypocalcemia ... Ifosfamide - Fanconi syndrome ... Trastuzumab • Hypokalemia ... Ifosfamide - Fanconi syndrome ... chemotherapy #diagnosis #differential
Treatment algorithm for malignancy-associated hypercalcemia.
Hypercalcemia
 - Renal Failure → Dialysis with low Ca++ bath
Aggressive IV hydration
malignancy-associated hypercalcemia ... Hypercalcemia - ... Dialysis with low ... malignancy #associated #hypercalcemia ... #management #endocrinology
BRASH Syndrome

B - Bradycardia
R - Renal failure
A - AV nodal blockade
S - Shock
H - Hyperkalemia

Typical ECG
S - Shock H - Hyperkalemia ... other findings of hyperkalemia ... of hyperkalemia ... #diagnosis #management ... #pathophysiology