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management causes nephrology high blood product rhabdomyolysis syndrome tls bradycardia constipation k leukostasis lysis oncology summary transfusion transfusions tumorlysis
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS Laboratory TLS: • Uric
Classification of Tumor ... 8.0 mg/dL • Potassium ... other symptomatic hypocalcemia ... hydroxide • Hyperkalemia ... • Hypocalcemia
Hyperkalemia Differential Diagnosis Algorithm R/O Pseudo-hyperkalemia: • Possible Lab error! Alwavs Repeat Blood sample! • Leukocytosis, Thrombocytosis:
Hyperkalemia Differential ... Diagnosis Algorithm ... R/O Pseudo-hyperkalemia ... plasma [K+] #Hyperkalemia ... Diagnosis #Algorithm
Hyperkalemia: Diagnostic algorithm Decreased renal potassium excretion • Acute renal failure • Chronic renal failure • Drugs Increased
Hyperkalemia: Diagnostic ... transfusion • Tumor ... • Type 1 #Hyperkalemia ... #Diagnosis #algorithm ... #differential
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... Suspicion for Hyperkalemia ... Drugs Causing Hyperkalemia ... Metabolic acidosis - Hyperkalemia ... cantaloupe #hyperkalemia
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... Suspicion for Hyperkalemia ... Drugs Causing Hyperkalemia ... Metabolic acidosis - Hyperkalemia ... images/12834 #hyperkalemia
Constipation - Differential Diagnosis Algorithm Diet/Lifestyle • Fibre • Calories • Fluid • Exercise • Psychosocial Medications •
Diagnosis Algorithm ... , Potassium) • ... Hypothyroidism • Hypokalemia ... • Hypercalcemia ... #Diagnosis #Algorithm
Hyperkalemia - Management Algorithm • IV calcium • IV insulin and glucose and/or salbutamolt • Consider
Hyperkalemia - Management ... calcium • IV ... , asystole #hyperkalemia ... #diagnosis #management ... #algorithm #treatment
Bradycardia Diagnostic and Management Algorithm CONSIDER ETIOLOGY (not inclusive): - STRUCTURAL: sick sinus, AV block, ischemia,
Bradycardia Diagnostic ... and Management Algorithm ... THREATENING CAUSES & TREATMENT ... Electrolytes (hyperkalemia ... #Differential
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
• LDH ↑ • Hyperkalemia ... Hyperphosphatemia • Hypocalcemia ... /Late - Hypercalcemia ... Monitor potassium ... Dialysis for severe hyperkalemia
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... hydration - Hyperkalemia ... treatment (no calcium ... Syndrome #TLS #diagnosis ... #management #hematology
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