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diagnosis algorithm causes oncology atlas mcv morphology rbc agglutinin bandemia bloodcell cold disease elevatedmcv gammopathies gap globulin hemolytic key macrocytosis
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Volume (MCV) - Differential ... • Drugs Oval Macrocytes ... Neutrophils - Low RBC ... Myelodysplastic Syndromes ... Algorithm #Causes #Hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
- Differential ... Spherocytosis, G6PD, PK, HbC ... Infections Macrocytic ... Folate deficiency, B12 ... #Diagnosis #hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
MCV - >96fL - "Macrocytic ... Megaloblastic: Vitamin B12 ... Myelodysplastic syndrome ... morphologic #mcv #differential ... diagnosis #causes #hematology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Lead poisoning • Macrocytic ... Myelodysplastic syndrome ... Hemolytic uremic syndrome ... key #diagnosis #differential ... #hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
) Morphology Microcytic ... (sometimes) Macrocytic ... RBC: Vitamin B12 ... #Morphology #differential ... #diagnosis #hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Megakaryopoiesis • Aplastic Anemia ... Megakaryopoiesis • B12 ... Non-lmmune: • HELLP Syndrome ... HUS • DIC • Vasculitis ... Algorithm #Causes #Hematology
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
Gammopathies C - HyperCalcemia ... Cr >2 mg/dL or CC ... 40 ml/min A - Anemia ... plasmacytoma, POEMs syndrome ... MGUS #diagnosis #hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
+Organomegaly+↑RBC ... Autoimmunity: • -MM/WM: Vasculitis ... (-) hemolytic anemia ... Paraproteinemias #Hematology ... #Monoclonal #Differential
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... Cold Agglutinin Syndrome ... Blood smear - RBC ... younger pts) Differential ... #hematology #diagnosis
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Neutrophil (Normal) Differential ... article/S0002-9343(12 ... #differential # ... #CBC #hematology ... #pathophysiology
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