14 results
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... of aspiration #Potassium ... #medications #pharmacology ... #table #comparison ... #binders
ACEI Antihypertensive Dose Comparison. Consider divided (BID) regimen for better pre-dose (trough) BP control for the
Monitor BP, potassium ... , and renal function ... ACEInhibitor #ACEIs #Dosing ... #Conversion #Pharmacology ... #Hypertension #
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Workup and Differential ... with previously stable ... disorders including hypokalemia ... Hyperthyroidism, Hypercalcemia ... #Workup #causes
Causes of Secondary Hypertension - Differential Diagnosis and Screening Testing
Common causes: 
 • Renal parenchymal disease
Hypertension - ... (correction of hypokalemia ... #Secondary #Hypertension ... #Screening #Workup ... #table
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Management Summary Causes ... injured muscles - HYPOTENSION ... fluid/Lactated ringers ... Monitor potassium ... per day until stable
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Digoxin Pharmacology ... Pump - Digoxin works ... intracellular calcium causes ... - Hyperkalemia ( ... Because digoxin binds
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
injured muscles -> HYPOTENSION ... Monitor potassium ... per day until stable ... Dialysis for severe hyperkalemia ... Management #Summary #causes
Lactated Ringers (LR) vs Normal Saline (NS) - Comparison

Composition of LR:
 • Sodium 130 mEq/L
 •
130 mEq/L • Potassium ... Is Dangerous in Hyperkalemia ... shift • Saline Causes ... • Saline May Cause ... NS #comparison #pharmacology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
reabsorption) Workup ... 15 suggests ↓ renal ... only if no clear cause ... Elimination (see Table ... Management #Treatment #potassium
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Torsemide) • Acute pulmonary ... Hyponatremia • Hypercalcemia ... Kidney stones caused ... Diuresis #Nephrology #Pharmacology ... #Medications #Table