35 results
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis
Causes of High-anion Gap Acidosis:
 • Lactic acidosis
Causes of High-anion ... of High-anion Gap ... , Pyroglutamic acid ... Acid loads (ammonium ... Metabolic #Acidosis #differential
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Algorithm Extra-renal ... Losses: • Normal Acid-Base ... Syndrome • HTN, High ... Diagnosis #Algorithm #causes
Hyperuricemia - Differential Diagnosis Algorithm
Primary - Over-production
     • Increased turnover of nucleotides
Primary
Hyperuricemia - Differential ... • Lower uric acid ... Drug-induced • High ... Sarcoidosis • Hypercalcemia ... endocrinology #causes
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
and sodium • Dosing ... and calcium • Dosing ... patients sensitive to high ... #medications #pharmacology ... #table #comparison
Classification, Differential Diagnosis, and Features of Hyponatremia According to Volume Status 

Hypervolemic hypernatremia 
 - CHF
Glucocorticoid deficit - Hypokalemia ... Drugs - SIADH Renal ... deficit - Salt-losing ... #Diagnosis #Table ... #Causes
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... Clenching of fist during ... phlebotomy High ... #differential # ... diagnosis #causes
Types of Renal Calculi

Calcium oxalate
 - Interstitial apatite plaque, Low urine volume, Increased urinary calcium excretion,
di-basic amino acids ... Mycoplasma infections, High ... magnesium Uric acid ... #stones #differential ... #diagnosis #causes
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... Clenching of fist during ... phlebotomy High ... #differential # ... diagnosis #causes
High Anion Gap Metabolic Acidosis (HAGMA) - Differential Diagnosis - GOLDMARK

Glycols - ethylene and propylene glycol
Oxoproline
High Anion Gap Metabolic ... L-lactate - produced during ... salicylate toxicity causes ... underexcretion of acids ... in advanced renal
Hypermagnesemia - Etiologies by Mechanism
Renal Failure 
Excessive Mg Administration 
 - Massive PO intake
by Mechanism Renal ... Hypermagnesemia #Differential ... #Diagnosis #High ... #Magnesium #Table ... #Causes #Management