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Drug-induced renal disorders - The most commonly used nephrotoxic drugs

#Pharmacology #Nephrotoxicity #Drugs #Medications #Most #Common #DrugInduced
Drug-induced renal ... #Medications #Most ... #DrugInduced #Acute ... #KidneyInjury #AKI ... #Table #List
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Pre-Renal:
 • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Acute Kidney Injury ... (AKI) - Differential ... Distributive Shock, HRS, Hypercalcemia ... Compartment Syndrome, Medications ... Pigment, Protein) • AIN
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
10 g QD (adjust dose ... Usual maintenance dose ... g QD; increase dose ... #medications #pharmacology ... #table #comparison
Medications causing Acute Kidney Injury (AKI)
Prerenal:
 • Dehydration: Diuretics
 • Altered intrarenal autoregulation: ACEIs / ARBs,
Medications causing ... Acute Kidney Injury ... (AKI) Prerenal: ... , tenofovir • AIN ... #Injury #Medications
Neonatal Resuscitation – Circulation and Drugs
Consider drugs (k) if heart rate beats/min in spite of adequate
(k) if heart rate ... Giving standard doses ... vasoconstriction may have had acute ... haemorrhage or acute ... #Medications #Pharmacology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Etiology: • Medications ... , RTA Type IV, AI ... Elimination (see Table ... STOP offending medications ... Transient, repeat dose
Pancreatitis management checklist 
Evaluation to guide etiology & management 
 - RUQ ultrasound 
 - Calcium
- Review of medication ... potentially causative drugs ... gram Q6hr) and pain-dose ... limit them as able ... Diagnosis #Management #CriticalCare
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
use of adequate doses ... with previously stable ... disorders including hypokalemia ... Hyperthyroidism, Hypercalcemia ... Differential #Diagnosis #indications
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Torsemide) • Acute ... Hyponatremia • Hypercalcemia ... hyperaldosteronism • Acute ... #Pharmacology #Medications ... #Table
Gout - Diagnosis and Management Summary

3 Conditions for Gout to Manifest:
1. Hyperuricemia
2. Monosodium urate deposition in
Metabolic syndrome • Medications ... swelling, significant pain ... comorbidities/drug ... NSAIDs • Low-dose ... dosage in CKD • Indications