21 results
Key Characteristics of Old and New Potassium-Binding Agents

- Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd

#Potassium #Binding #KBinders #Kayexelate
Agents - Dr. ... Kayexelate #Comparison #Table ... #Pharmacology # ... Patiromer #HyperKalemia ... #Nephrology #Agents
Therapeutic Indications for the Anticonvulsant Agents

#Anticonvulsant #Antiseizure #Medications #Pharmacology #Table #Neurology #Epilepsy #Management
Therapeutic Indications ... Anticonvulsant Agents ... #Antiseizure #Medications ... #Pharmacology # ... Table #Neurology
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... #differential #diagnosis ... pathophysiology #pharmacology ... #potassium #medications ... #druginduced
Antiarrhythmic Medications - Vaughan Williams Classification - Summary Table
Class I agents - Sodium Channel Blockers⠀
Class II
Antiarrhythmic Medications ... Classification - Summary Table ... - Potassium Channel ... Antiarrhythmic #Medications ... #pharmacology #
Summary of Diuretic Agents 
Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction
CARBONIC ANHYDRASE
Summary of Diuretic Agents ... #Diuretics #Medications ... #Pharmacology # ... summary #table # ... nephrology
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... Agents to Treat ... of aspiration #Potassium ... #medications #pharmacology ... #table #comparison
Potassium Binders for Management of Hyperkalemia
 • SPS - Sodium polystyrene sulfonate
 • Patiromer (veltassa)
 •
Potassium Binders ... Management of Hyperkalemia ... #treatment #pharmacology ... #table #comparison ... #nephrology
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Hypokalemia - Differential ... Diagnosis Algorithm ... Thyrotoxicosis Medications ... #Algorithm #nephrology ... #low #potassium
Drug Induced Kidney Injury
 • Pre-Renal: NSAIDS, CNI, ACEI/ARB, IL-2 therapy, Diuretics CAR-T therapy
 • Osmotic
Mannitol, Contrast agents ... @kdjhaveri #DrugInduced ... #differential #diagnosis ... #algorithm #nephrology ... #Medications
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Diagnosis Framework ... • Recent IV potassium ... Medications 2. ... #causes #potassium ... #high #nephrology