1352 results
Cutaneous signs of Addison's disease may be a useful clue. Hyperpigmentation especially involves sun-exposed areas and
Cutaneous signs ... Hyperpigmentation ... often have patchy hyperpigmentation ... flexural on oral hyperpigmentation
Generalized Hyperpigmentation Differentials
Use the Mnemonic "no skin SPARED"

Images from dermnet.nz and merckmanuals

Mnemonic from https://www.medscape.com/slideshow/dermatology-mnemonics-6011359#5 #diagnosis #differential
Generalized Hyperpigmentation ... differential #symptoms #signs
Thyroid Eye Signs 
Lid Signs
    Dalrymple’s Sign: Lid Retraction.
    Von
Thyroid Eye Signs ... Lid Signs ... Dalrymple’s Sign ... Von Graefe’s Sign ... : Hyperpigmentation
Symptoms and Signs of Hypocalcemia
Muscular: Weakness, fatigue, Spasms, cramps
Neurologic: Tetany, Chvostek sign, Trousseau sign, Circumoral and
Symptoms and Signs ... Tetany, Chvostek sign ... , Trousseau sign ... Dermatologic: Hyperpigmentation ... Hypocalcemia #Symptoms #Signs
CLINICAL MANIFESTATIONS 
OF ADRENAL INSUFFICIENCY. 

Primary and secondary adrenal insufficiency:
 - Tiredness, weakness, mental depression
disorders: - Hyperpigmentation ... Insufficiency #Signs
Congenital Adrenal Hyperplasia - 21-Hydroxylase Deficiency - Signs and Symptoms
 • Brain: Androgenization effects, Glucocorticoid effects,
Hydroxylase Deficiency - Signs ... failure • Skin: Hyperpigmentation ... Hydroxylase #Deficiency #Signs
Physiologic Skin Changes in Pregnancy - Differential Diagnosis Algorithm

Face
 • Melasma
Abdomen
 • Linea Nigra 
Hormone induced
Hormone induced • Hyperpigmentation ... • Chadwick's sign
Disorders of Pigmentations - Hypopigmentation and Hyperpigmentation - Differential Diagnosis Algorithm

HYPOPIGMENTATION
Diffuse Congenital - Generalized hypopigmentation of
Pigmentations - Hypopigmentation ... and Hyperpigmentation ... HYPERPIGMENTATION ... #Hypopigmentation ... #Hyperpigmentation
Primary Adrenal Insufficiency
Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
vomiting • Fatigue Signs ... Cortisol Deficiency: Signs ... • Hyperpigmentation ... Reduced libido • Signs ... endocrinology #diagnosis #signs
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
failure PBC Signs ... Examination: • Skin hyperpigmentation