343 results
Causes of Hyperuricemia
Increased production
 • Solid-organ transplant
 • Tumor lysis syndrome
 • Rhabdomyolysis
 • Lesch Nyhan
Causes of Hyperuricemia ... Functionally normal kidneys ... Associated with chronic kidney ... protein in the kidney ... uric acid #Hyperuricemia
Hyperuricemia: Pathogenesis and Complications

 - Hypercalcemia (due to diseases like Sarcoidosis and Hyperparathyroidism) -> Accumulation of
Hyperuricemia: Pathogenesis ... decr ability of kidneys ... uric acid >> Hyperuricemia ... the blood #Hyperuricemia
Types of Renal Calculi

Calcium oxalate
 - Interstitial apatite plaque, Low urine volume, Increased urinary calcium excretion,
amino acids in kidney ... Uric acid - Hyperuricemia ... - Hyperuricemia
Management of Pediatric Kidney Stones
Acute Managment:
 • Pain relief: NSAIDs, opioids
 • Facilitating passage of stone:
Management of Pediatric Kidney ... : Liver and/or kidney ... : Lumasiran • HYPERURICEMIA ... SwastiThinks #Kidney
Metabolic Causes of Kidney Stones in Children
 • Calcium Oxalate: Primary Hyperoxaluria type 1-3, Secondary Hyperoxaluria
Metabolic Causes of Kidney ... superactivity, Secondary Hyperuricemia ... Metabolic #Causes #Kidney
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Hypercalcemia • Hyperuricemia ... nephrotoxicity to kidney ... Allopurinol for hyperuricemia
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
tubule of the kidney ... Metabolic: - Hyperuricemia
NSAID vs ACEI/ARB effects on the Kidneys

Remember that NSAIDs and ACEI/ARB therapy have opposing effects on
effects on the Kidneys ... effects on the kidneys ... contribute to kidney ... patients with normal kidney ... used for their kidney
TB Man - Mnemonic for Anti-Tuberculosis Medication Toxicities
Isoniazid - peripheral neuropathy, neurotoxicity, hepatotoxicity
Streptomycin - ototoxicity
Ethambutol -
Pyrazinamide - hyperuricemia
Hyperuricemia - Differential Diagnosis Algorithm
Primary - Over-production
     • Increased turnover of nucleotides
Primary
Hyperuricemia - ... gout #UricAcid #Hyperuricemia