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diagnosis differential management causes rheumatology workup hematology lupus pediatrics peds treatment dermatology disorders nephrology vasculitis chronic kawasaki pulmonary secondary systemic
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... Chain deposition disease ... @AnnKumfer #Hypocomplementemia ... #Low #Complement
Effect of Selected Diseases on Complement Levels - C3, C4 • SLE C3 ↓ C4 ↓↓
Effect of Selected Diseases ... on Complement Levels ... - C3, C4 • SLE ... • Infection eg SBE ... ThePeanutKidney #Complement
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE ... are evocative of SLE ... 80% - Low complement ... • Evolution: ... Chronic disease
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
90% - Low complement ... cutaneous-DIL • Evolution ... 80% - Low complement ... • Evolution: ... Chronic disease
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis 90%: -
Vasculitis - Anti-GBM Disease ... anti-GBM) 10%: - Low Complement ... Levels: SLE, Cryoglobulinemic ... Vasculitis - Normal Complement ... , mitral valve disease
Algorithm for the Evaluation and Management of Suspected Congenital Heart Disease in Neonates Neonates with undiagnosed congenital
Algorithm for the ... Evaluation and ... Congenital Heart Disease ... congenital heart disease ... #HeartDisease #Algorithm
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... (Granulomatous disease ... against MPO • Complement ... vasculitis, and SLE
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
staining): • Low Complement ... Idiopathic • Normal Complement ... involvement: Anti-GBM Disease ... differential #diagnosis #algorithm
Algorithm for diagnostic evaluation of patients with kidney cysts and polycystic kidney disease #polycystic #kidney #disease #cysts
Algorithm for diagnostic ... evaluation of patients ... polycystic kidney disease ... polycystic #kidney #disease ... #cysts #Algorithm
The Diagnostic Approach to Hyperkalemia Drugs - Amiloride - Spironolactone - Triamterene - Trimethoprim - Pentamidine -
Tubulointerstitial diseases ... - Sickle cell disease ... transplant - SLE ... Tubulointerstitial diseases ... #Hyperkalemia #Algorithm
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