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diagnosis differential rheumatology dermatology disorders hypopigmentation skin cryoglobulinemia cryoglobulins dermatitis erythema erythematosus gammopathy glomerulonephritis hyperpigmentation lupus mgrs monoclonal palm petechiae
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... Urticaria and hypocomplementemia ... mucositis - Rash ... against MPO • Complement ... #classification
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... staining): • Low Complement ... Glomerulonephritis #Vasculitis ... differential #diagnosis #algorithm ... #rheumatology
Skin Hypopigmentation - Differential Diagnosis Algorithm Diffuse Congenital - Generalized hypopigmentation of hair, eyes, skin • Phenylketonuria
Diffuse Congenital ... • Piebaldism Diffuse ... sclerosis (white "ash ... disorders #skin #dermatology ... #causes
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Diagnosis Algorithm ... Infection - Vasculitis ... - Autoimmune Vasculitis ... #Causes #dermatology
Disorders of Pigmentations - Hypopigmentation and Hyperpigmentation - Differential Diagnosis Algorithm HYPOPIGMENTATION Diffuse Congenital - Generalized hypopigmentation of
Differential Diagnosis Algorithm ... sclerosis (white "ash ... disorders #skin #dermatology ... Differential #Diagnosis #Algorithm ... #causes
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low complements ... Skin Disease Classification ... pneumonitis • Diffuse ... enteropathy, and diffuse ... RNP antibodies, Complement
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... • Low serum C4 complement ... diagnosis #types #classification ... #rheumatology #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
, mucositis • Rash ... tract, and often causes ... Elevated AST ALT • Hypocomplementemia ... ) • Hypocomplementemic ... Differential #Diagnosis #Rheumatology
PALM RASHES Common features and patterns: 1. Color: o Red or erythematous: Common in inflammatory or allergic reactions. o Purple or purpuric:
suggest vascular or hematologic ... inflammation (vasculitis ... Seen in systemic causes ... disease. 6 Causes ... Drug Reactions: Diffuse
Monoclonal Gammopathy of Renal Significance (MGRS) MGRS • MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
kidney disease caused ... meet criteria for hematologic ... guide subtype classification ... tubulopathy) - Complement ... formation causing vasculitis
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