12 results
diagnosis differential nephrology rheumatology glomerulonephritis renal lupus management sle testing vasculitis aki causes classification comparison druginduced erythematosus gammopathy hematology hematuria
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
formation along glomerular ... staining (lg + complement ... MGPN • Complement ... (Dense deposit disease ... glomerulopathy, radiation nephritis
Causes of Hematuria - Differential Diagnosis Algorithm Red blood cells on urine microscopy. Must exclude false positives
Differential Diagnosis Algorithm ... • Thin GBM disease ... • Hereditary nephritis ... • Pauci-immune disease ... and >3.5g/day (nephrotic
Recommended initial testing for patients being evaluated for glomerular disease 24-hour urine collection - Quantify proteinuria.
disease 24- ... or alternative complement ... disease. ... #testing #workup ... #nephritic #nephrology
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Algorithm - Approach ... impairment), heart disease ... clusters because nephritic ... #Algorithm #differential ... #proteinuria #nephrotic
Recommended initial testing for patients being evaluated for glomerular disease 1) 24-hour urine collection - Quantify proteinuria.
or alternative complement ... #glomerular #disease ... #workup #diagnosis ... testing #nephrology #nephrotic ... #nephritis
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
staining): • Low Complement ... Post-strep GN, Lupus Nephritis ... Idiopathic • Normal Complement ... involvement: Anti-GBM Disease ... differential #diagnosis #algorithm
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitis - Skin, glomeruli ... often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... : - Kidneys: glomerular ... against MPO • Complement
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
ulcers, Lupus nephritis ... • Immunologic Workup ... 80% - Low complement ... Evolution: Chronic disease
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Differential Diagnosis Algorithm ... hematology for workup ... Vasculitides, IBD, Celiac disease ... , Kawasaki, Nephrotic ... Differential #Diagnosis #Algorithm
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... 90% - Low complement ... ulcers, Lupus nephritis ... • Immunologic Workup ... Evolution: Chronic disease
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