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diagnosis hematology differential management blood intravascular product reactions anosmia coagulation dermatology disseminated extravascular fever hemolysis hus immunecompromised immunocompromised loss microangiopathy
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... Differential Diagnosis Algorithm ... • PK deficiency ... perfringens - Complement-Mediated ... • MAHA (TTP, DIC
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
: • Platelet count ... Thrombocytopenia - Platelet ... thrombopoietin deficiency ... Treat primary cause ... Coagulation #diagnosis #causes
Thrombotic Microangiopathy - TMAs 1. Not all MAHAs are due to TMAs but (almost) all TMAs cause
almost) all TMAs cause ... is due to TTP, compliment-mediated ... children, so I did ... significant renal dysfunction ... Cr>2.3 & platelets
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Differential Diagnosis Algorithm ... Thrombocytopenia - Abnormal platelet ... Clotting factor deficiency ... fulminans - DIC
Anosmia / Smell Dysfunction - Differential Diagnosis Algorithm Nasal Obstruction/ URTI: • Septal Deviation • Allergic Rhinitis
Anosmia / Smell Dysfunction ... Differential Diagnosis Algorithm ... Deviation • Allergic ... • Zinc Deficiency ... #Causes
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
pain, dark urine, DIC ... - Allergic ... recipients w/ IgA deficiency ... Causes purpura & ... TRALI): Leading cause
Causes of Fever in the Immunocompromised Host - Differential Diagnosis Algorithm Structural Defect - Asplenia/HypospIenism • Bacteremia/Septic
Causes of Fever ... or Neutrophil Dysfunction ... Periodontal Disease Complement ... Deficiency • ... #Causes #Hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
pain, dark urine, DIC ... • Allergic reaction ... recipients w/ IgA deficiency ... Causes purpura & ... TRALI): Leading cause
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