12 results
diagnosis differential hematology causes vasculitis immunology rheumatology testing anosmia c1inh c5c9deficiency classification dysfunction esterase extravascular fever glomerulonephritis hemolysis henochscholeinpurpura hsp
Pathophysiology of Hypocomplementemic Urticarial Vasculitis C1q/anti-C1q antibiody -> Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Pathophysiology ... of Hypocomplementemic ... Complex Formation - Complement ... TerrierBen #Hypocomplementemic ... Vasculitis #HUV #Pathophysiology
C5-C9 Deficiency - Pathogenesis and Clinical Findings Note: • Risk of invasive meningococcal disease is 1000-10000x higher
C5-C9 Deficiency ... higher in C5-C9 deficiency ... is rare Normal complement ... response: The complement ... #pathophysiology
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
When the specific allergen ... antigen, leading to complement ... Complement activation ... Classification #Pathophysiology ... #Allergy #Diagnosis
Complement 1 esterase inhibitor (C1-INH) Deficiency Testing Algorithm INDICATIONS FOR TESTING: • Recurrent angioedema (without urticaria) •
Complement 1 esterase ... inhibitor (C1-INH) Deficiency ... Testing Algorithm ... #Testing #Algorithm ... #allergy #diagnosis
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Differential Diagnosis Algorithm ... Defects • G6PD deficiency ... • PK deficiency ... perfringens - Complement-Mediated ... Differential #Diagnosis #Algorithm
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
three primary pathophysiologic ... staining): • Low Complement ... Idiopathic • Normal Complement ... differential #diagnosis #algorithm
Complement Deficiency Testing Algorithm • Normal CH50 and AH50 AND High suspicion for complement deficiency •
Complement Deficiency ... Testing Algorithm ... suspicion for complement ... deficiency • Low ... #Algorithm #hematology
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings - Infectious Agents - 50% have
Circulating galactose-deficient ... Deficiency in galactosylation ... Activation of complement ... HenochScholeinPurpura #Pathophysiology
Type II Hypersensitivity: Pathogenesis and clinical findings Definition: When antigens bind to the body's cell surfaces, forming
activates the complement ... HypersensitivityReaction #Allergy ... #Immunology #pathophysiology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Differential Diagnosis Algorithm ... Acute hemolysis, deficiency ... post-splenectomy, Exercise, Allergic ... Differential #Diagnosis #Algorithm
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