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diagnosis differential hematology causes types anemia hypersensitivity reactions rheumatology table testing angioedema anosmia approach c1inh comparison dysfunction erythematosus esterase extravascular
Angioedema - Classification Diagnosis and Treatment Types of Angioedema: • Acute allergic angioedema - Usually occurs with
Angioedema - Classification ... Angioedema: • Acute allergic ... exposure • Non-allergic ... Acquired C1 inhibitor deficiency ... #Angioedema #Classification
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
Soluble antigen - Allergen-specific ... When the specific allergen ... antigen, leading to complement ... Complement activation ... Hypersensitivity #Types #Classification
Complement 1 esterase inhibitor (C1-INH) Deficiency Testing Algorithm INDICATIONS FOR TESTING: • Recurrent angioedema (without urticaria) •
Complement 1 esterase ... inhibitor (C1-INH) Deficiency ... Testing Algorithm ... #Testing #Algorithm ... #allergy #diagnosis
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Mechanism of Action: Allergen-specific ... antigens, leading to complement ... they activate complement ... reactions #types #allergy ... #table #classification
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Differential Diagnosis Algorithm ... Defects • G6PD deficiency ... • PK deficiency ... perfringens - Complement-Mediated ... Differential #Diagnosis #Algorithm
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Differential Diagnosis Algorithm ... 80 fL) • Iron Deficiency ... • Folate Deficiency ... #Anemia #MCV #Classification ... Differential #Diagnosis #Algorithm
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Differential Diagnosis Algorithm ... Reticulocytes • Iron Deficiency ... • B12/Folate Deficiency ... Non-lmmune #Anemia #Classification ... Differential #Diagnosis #Algorithm
Complement Deficiency Testing Algorithm • Normal CH50 and AH50 AND High suspicion for complement deficiency •
Complement Deficiency ... Testing Algorithm ... suspicion for complement ... deficiency • Low ... #Algorithm #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... against MPO • Complement ... #rheumatology #classification
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Differential Diagnosis Algorithm ... Acute hemolysis, deficiency ... post-splenectomy, Exercise, Allergic ... Differential #Diagnosis #Algorithm
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