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diagnosis differential hematology causes hemolytic pulmonary systemic agglutinin approach autoimmune comparison dermatology disease erythematosus extravascular functiontests groups hemolysis hypertension interpretation
Warm vs Cold Autoimmune Hemolytic Anemia Warm Autoimmune Hemolytic Anemia: • Mechanism: IgG and Complement-mediated • Etiology:
Warm vs Cold Autoimmune ... Mechanism: IgG and Complement-mediated ... Lymphoproliferative disorder ... , Autoimmune disorder ... Mechanism: IgM and Complement-mediated
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
lymphoproliferative disorder ... infection, autoimmune disorder ... • Symptoms of anemia ... • hemolytic anemia ... temperatures by fixing complement
Pulmonary Function Tests (PFTs) - Interpretation Algorithm • Normal • Pulmonary Hypertension, Anemia, Carboxyhemoglobinemia • Chest
Interpretation Algorithm ... Hypertension, Anemia ... Neuromuscular Disorders ... Emphysematous COPD ... Interpretation #Algorithm
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Differential Diagnosis Algorithm ... Warm AIHA • Cold ... perfringens - Complement-Mediated ... • Cold AIHA ... immune-complex hemolytic anemia
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Differential Diagnosis Algorithm ... • RBC Membrane Disorder ... RBC Metabolism Disorder ... #Classification ... Differential #Diagnosis #Algorithm
Pulmonary Hypertension Groups - WHO Classification Group I - Vascular remodeling of pulmonary arteries • Idiopathic, HIV,
connective tissue disorders ... hypoxemia • COPD ... chronic hemolytic anemia ... , thyroid disorders ... , sickle cell anemia
Hematology Algorithms Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... Anemia is described ... involves production disorders ... that involves disorders ... These causes could
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Differential Diagnosis Algorithm ... Agglutination - Cold ... Consider RBC membrane disorder ... ARUPLabs #Hemolytic #Anemia
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Nail Disorders secondary ... Diseases Nail Fold ... Iron deficiency anemia ... renal failure • Uremia ... Differential #Diagnosis #Algorithm
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low complements ... Skin Disease Classification ... ) • Endocrine disorders ... lymphopenia, low PLT • Anemia ... RNP antibodies, Complement
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