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diagnosis differential rheumatology anemia dermatology erythematosus lupus systemic vasculitis allergy approach clinicopathology comparison criteria effusions eularacr extravascular hemolysis hypersensitivity immunecompromised
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Constitutional domain: Fever ... discoid lupus, Acute ... anticoagulant • Complement ... #Criteria #SLE
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... Differential Diagnosis Algorithm ... perfringens - Complement-Mediated ... anemia • Acute ... #Causes #Hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
disorders, or other causes ... Coagulation disorders CAUSES ... Quantity: • Primary Causes ... • Secondary Causes ... Gardner-Diamond syndrome CAUSES
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... Differential Diagnosis Algorithm ... RA, SLE, PRV, Chronic ... Normal RBCs • Acute ... #Causes #Hematology
Primary Dermatologic Nail Disorders - Differential Diagnosis Algorithm Nail Plate - Pitting • Psoriasis • Alopecia Areata Nail
Differential Diagnosis Algorithm ... Trauma/lnfection - Acute ... Telangiectasia • SLE ... NailDisorders #Primary #dermatology ... #causes
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Differential Diagnosis Algorithm ... Blood Loss • Acute ... Non-lmmune #Anemia #Classification ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... Vasculitis: • Fevers ... against MPO • Complement ... vasculitis, and SLE ... #classification
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... anti-Smith Ab, low complements ... Skin Disease Classification ... : • Acute cutaneous ... to: Arthritis, Fever
Causes of Knee Effusions - Differential Diagnosis Framework Knee Effusion Red Flags: 1. Fever/Chills/Joint pain/Night sweats/Weight loss - DDX: -
Causes of Knee Effusions ... Fever/Chills/Joint ... arthritis - SLE ... Reactive Syndrome - Acute ... Knee #Effusions #causes
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Allergen-specific lgE causes ... Anaphylaxis, Hay fever ... days - Examples: Acute ... they activate complement ... allergy #table #classification
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