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rheumatology erythematosus management differential systemic criteria druginduced vasculitis antidsdna arthritis biomarkers causes classes clinicopathology comparison cryoglobulinemia cryoglobulins dil disease eularacr
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus Clinical and Immunologic Criteria CLINICAL CRITERIA - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... ANA level above laboratory ... antibody level above laboratory ... anticoagulant - Low complement ... #Rheumatology #SLE
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... (SLE) - Diagnosis ... versus DIL • Laboratory ... 80% - Low complement ... Erythematosus #Diagnosis
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
calcium-b) • Laboratory ... 90% - Low complement ... versus DIL • Laboratory ... 80% - Low complement ... #rheumatology #diagnosis
Lupus - Role of complement and anti-dsDNA for the detection of flares Complement - ↓ Decreased Anti-dsDNA -
Lupus - Role of ... complement and anti-dsDNA ... Increased #Lupus ... #SLE #flares #laboratory ... #diagnosis #rheumatology
Lupus Nephritis Primer Class I - Minimal Mesangial Class II - Mesangial Proliferative Class Ill - Focal Proliferative Class IV
Lupus Nephritis ... Proliferative Class IV - Diffuse ... #Nephritis #SLE ... #Classification ... #differential #diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... and fever) and laboratory ... anti-Smith Ab, low complements ... Skin Disease Classification ... Differential Diagnosis
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... anticoagulant • Complement ... #EULARACR #Classification ... #Criteria #SLE ... Erythematosus #diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
inflammation Others: • Lupus ... such as systemic lupus ... against MPO • Complement ... vasculitis, and SLE ... #rheumatology #classification
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
joint • Systemic lupus ... more time for the laboratory ... Screening Tests for Diffuse ... (to support a diagnosis ... #workup #diagnosis
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Labs/Diagnosis: ... • Low serum C4 complement ... (e.g. systemic lupus ... erythematosus (SLE ... #types #classification
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