11 results
diagnosis rheumatology vasculitis algorithm hematology types acidosis allergy causes champs disorders druginduced edema erythematosus glomerulonephritis humoral huv hypersensitivity hypocomplementemic igg4
Pathophysiology of Hypocomplementemic Urticarial Vasculitis C1q/anti-C1q antibiody -> Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Pathophysiology ... of Hypocomplementemic ... Complex Formation - Complement ... TerrierBen #Hypocomplementemic ... Vasculitis #HUV #Pathophysiology
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... @AnnKumfer #Hypocomplementemia ... #Low #Complement ... Mnemonic #diagnosis #differential
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
three primary pathophysiologic ... staining): • Low Complement ... Idiopathic • Normal Complement ... Glomerulonephritis #Vasculitis #differential
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
antigen, leading to complement ... Complement activation ... Hypersensitivity #Types #Classification ... #Pathophysiology
Humoral Immunity - Pathogenesis and Clinical Findings Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
activation • Complement ... tagged with C3 complement ... - Activate Complement ... proliferate and differentiate ... Humoral #Immunity #pathophysiology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitides - Differential ... often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... against MPO • Complement ... #rheumatology #classification
Drug-Induced Edema Drug-induced edema is caused by many drugs & can coincide with or worsen pre-existing peripheral
Activation of the complement ... Medication #Causes #Differential ... #Pharmacology #Pathophysiology
Lactic Acidosis - Overview and Pathophysiology Lactic acid is an endogenous substrate for gluconeogenesis, that is constantly
- Overview and Pathophysiology ... Acidosis #types #differential ... #diagnosis #pathophysiology ... #classification
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders - Differential ... Lymphoproliferative #Disorders #Classification ... #pathophysiology ... Diagnosis #NonHodgkin #differential
IGG-4 RELATED DISEASE WHAT? • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
dysfunction PATHOPHYSIOLOGY ... - ↑ IgE, ↓ complement ... • Classification
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