11 results
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... staining): • Low Complement ... Idiopathic • Normal Complement ... differential #diagnosis #algorithm
Drug-Induced Edema
Drug-induced edema is caused by many drugs & can coincide with or worsen pre-existing peripheral
Drug-induced edema is caused ... blood vessels, leading ... Activation of the complement ... Edema #Medication #Causes ... #Pharmacology #Pathophysiology
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
cellular antigen, leading ... to complement activation ... Complement activation ... Hypersensitivity #Types #Classification ... #Pathophysiology
Hyperkalemia Differential Diagnosis Algorithm
R/O Pseudo-hyperkalemia:
 • Possible Lab error! Alwavs Repeat Blood sample!
 • Leukocytosis, Thrombocytosis:
Differential Diagnosis Algorithm ... tourniquet while drawing ... Differential #Diagnosis #Algorithm ... #causes #potassium ... #high #pathophysiology
Shock Classification Types - Pathophysiology Comparison

Obstructive Shock:
 • Obstructive shock is characterized by a blockage in
Shock Classification ... Types - Pathophysiology ... in blood flow caused ... Depends on the cause ... external fluid loss leading
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Allergen-specific lgE causes ... cell antigens, leading ... to complement activation ... they activate complement ... allergy #table #classification
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... Low Grade - Slow growing ... Lymphoproliferative #Disorders #Classification ... #pathophysiology ... #differential #algorithm
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... against MPO • Complement ... #rheumatology #classification
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Differential Diagnosis Algorithm ... Cause - Decreased ... gastrointestinal osmotic gradient ... Differential #Diagnosis #Algorithm ... #Pathophysiology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
immune system, leading ... • They can cause ... Cryoglobulins Cause ... • Low serum C4 complement ... diagnosis #types #classification