11 results
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Allergen-specific lgE causes ... cell antigens, leading ... to complement activation ... they activate complement ... allergy #table #classification
Hemolysis Classification - Intrinsic and Extrinsic Causes

Commentary: Another way to think of immune hemolysis would be
Hemolysis Classification ... and Extrinsic Causes ... hemolytic transfusion reactions ... #Hemolysis #Classification ... #Algorithm
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
cellular antigen, leading ... Complement activation ... Hypersensitivity #Types #Classification ... #Pathophysiology ... Allergy #Diagnosis #Reactions
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... staining): • Low Complement ... Idiopathic • Normal Complement ... differential #diagnosis #algorithm
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... are present • Classic ... Lymphoproliferative #Disorders #Classification ... #pathophysiology ... #differential #algorithm
Drug-Induced Edema
Drug-induced edema is caused by many drugs & can coincide with or worsen pre-existing peripheral
blood vessels, leading ... Activation of the complement ... Edema #Medication #Causes ... #Pharmacology #Pathophysiology
Hyperkalemia Differential Diagnosis Algorithm
R/O Pseudo-hyperkalemia:
 • Possible Lab error! Alwavs Repeat Blood sample!
 • Leukocytosis, Thrombocytosis:
Differential Diagnosis Algorithm ... tourniquet while drawing ... Differential #Diagnosis #Algorithm ... #causes #potassium ... #high #pathophysiology
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
degranulation, leading ... cell surfaces causes ... , leading to an ... exposure to allergen causes ... #Types #Classification
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... Urticaria and hypocomplementemia ... disease, drug reactions ... against MPO • Complement ... #rheumatology #classification
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
channels open leading ... channels open leading ... Vaughan Williams Classification ... #Pharmacology #Classification ... #Classes #pathophysiology