12 results
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... S - Systemic Lupus ... @AnnKumfer #Hypocomplementemia ... #Low #Complement
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
Rapidly Progressive ... staining): • Low ... GN, Lupus Nephritis ... With associated pulmonary ... differential #diagnosis #algorithm
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework
Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis
90%:
 -
Pulmonary Renal ... Diagnosis Framework Diffuse ... alveolar hemorrhage + rapidly ... anti-GBM) 10%: - Low ... Complement Levels
Causes of Hemoptysis - Differential Diagnosis Algorithm
Massive Hemoptysis (>I00 mL in 24 hours)
 • Malignancy
 •
Differential Diagnosis Algorithm ... • Bronchitis Diffuse ... Vasculitis • Lupus ... Differential #Diagnosis #Algorithm ... #Causes #Pulmonary
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
, proteinuria, rapidly ... inflammation Others: • Lupus ... such as systemic lupus ... against MPO • Complement ... (Low levels mixed
Hypoxemia / Hypoxia - Rapid Response Management Algorithm

Stridor - Upper airway pathology:
 • Anaphylaxis
 • Foreign
Hypoxemia / Hypoxia - Rapid ... Response Management Algorithm ... pathology: • Blood: diffuse ... pneumonia • Water: pulmonary ... #rapid #pulmonary
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
non-specific, ESR usually low ... capillaritis leading to diffuse ... hemorrhage (DAH) • Diffuse ... hematuria, RBC casts, low ... proteinuria • Path: rapidly
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low ... complements and ... pneumonitis • Diffuse ... enteropathy, and diffuse ... , lymphopenia, low
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... lymphadenopathy more diffuse ... B-Cell ~90% • Low ... correlated with rapid ... #differential #algorithm
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
joint • Systemic lupus ... (3) Rises more rapidly ... Screening Tests for Diffuse ... Additional Tests for Diffuse ... chest wall, and low