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diagnosis rheumatology classification hematology vasculitis champs clinicopathology comparison disorders dysphagia erythematosus gastroenterology glomerulonephritis laboratory lymphomas lymphoproliferative management mimics mnemonic myopathies
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... S - Systemic Lupus ... @AnnKumfer #Hypocomplementemia ... #Low #Complement ... Mnemonic #diagnosis #differential
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Rapidly Progressive ... staining): • Low ... GN, Lupus Nephritis ... Glomerulonephritis #Vasculitis #differential ... #diagnosis #algorithm
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis 90%: -
Syndromes and Mimics - Differential ... Diagnosis Framework Diffuse ... hemorrhage + rapidly progressive ... anti-GBM) 10%: - Low ... Complement Levels
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
Polymyositis • Progressive ... Dermatomyositis • Progressive ... Body Myositis • Slow ... Myopathy • Diffuse ... Myopathies #myopathy #differential
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Diagnosis Algorithm ... system (node) with progression ... lymphadenopathy more diffuse ... B-Cell ~90% • Low ... #algorithm
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
proteinuria, rapidly progressing ... inflammation Others: • Lupus ... such as systemic lupus ... against MPO • Complement ... (Low levels mixed
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low ... complements and ... permanent alopecia Differential ... pneumonitis • Diffuse ... , lymphopenia, low
Dysphagia - Differential Diagnosis Framework Symptom | Diagnosis • Solid-food dysphagia present for months to years | Mechanical
Dysphagia - Differential ... Schatzki ring) • Progressively ... Intermittent: Diffuse ... region • Bolus slow ... #Dysphagia #Differential
6/02/2022 UPDATE: This assay is designed to detect non-variola orthopoxviruses, including monkeypox virus. It is not
monkeypox virus or to differentiate ... should use this algorithm ... risk of smallpox –low ... specimens from low ... depending upon disease progression
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