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diagnosis rheumatology differential management sle table classification druginduced erythematosus hematology systemic vasculitis champs differences dil disorders ebm fever glomerulonephritis hypothermia
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... S - Systemic Lupus ... @AnnKumfer #Hypocomplementemia ... #Low #Complement
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
in >90% - Low ... complement - Rare ... 60-80% - Low ... complement - 50 ... #sle #comparison
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
staining): • Low ... Complement: Post-strep ... GN, Lupus Nephritis ... Idiopathic • Normal Complement ... differential #diagnosis #algorithm
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... , oral ulcers, Lupus ... 60-80% - Low ... complement - 50 ... life-threatening • Treatment
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
Body Myositis • Slow ... Anti-retrovirals, Gemcitabine Lupus ... Myopathy • Diffuse ... uncommon 5-15% of lupus ... differential #diagnosis #comparison
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low ... complements and ... pneumonitis • Diffuse ... enteropathy, and diffuse ... , lymphopenia, low
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... lymphadenopathy more diffuse ... B-Cell ~90% • Low ... Responsive to Treatment ... #differential #algorithm
What is the difference between ischemic colitis and mesenteric ischemia? A common misnomer. Mesenteric ischemia and ischemic
scripts and initial treatment ... algorithms. ... to nonocclusive low ... flow states • ... mesentericischemia #comparison
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Urticaria and hypocomplementemia ... inflammation Others: • Lupus ... such as systemic lupus ... against MPO • Complement ... (Low levels mixed
Comparison of Fever Algorithms for Infants <3 months old AGE, INCLUSION, TESTS REQUIRED, "LOW RISK" CRITERIA, TREATMENT,
Comparison of Fever ... Algorithms for ... TESTS REQUIRED, "LOW ... RISK" CRITERIA, TREATMENT ... #Comparison #Table
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